If you had your tonsils out as a teenager or after having a baby, hemorrhaged a lot, you may forget about these bleeding problems in the past. Those are very, very subtle clues that can lead a doctor to order a Von Willebrand's assay. These are very expensive tests and certainly not every woman needs it. But if a woman bruises easy, nose bleeds, brushing your teeth, gums bleed very easily, paper cuts that don't stop -- those are the signals in our history taking that would say, "You know maybe this $300 test would be helpful." But I don't want women to think that every woman needs this particular assay. But certainly if you're noticing some changes, we should look for those.
And also, a lot of women are using herbal products now. Some multibillion-dollar business and I think some of the herbs are associated with problems that can lead to bleeding. Lots of women are using aspirin and if you're taking anything over the counter, you want to let your physician know because these other things can also lead to bleeding. It's not always the uterus.
What do they say? You can't see the forest for the trees or we get so focused on just the uterus, but there can be other things systemically that cause the problem.
KEITH ISAACSON, MD: The key is that most of this can be determined by a good history when you first see a patient. So if they have a regular cycle, then it's unlikely that they have hormonal problem. And therefore if it's regular cycle, these are very good candidates and the patient should be offered a diagnostic hysteroscopy in the office.