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Diet and Weight Loss Diet

Live Longer Without Starving?


Author:

Eric Sabo

Medically Reviewed On: May 31, 2005

You may not have to starve yourself to live forever, according to a new study that tinkered with the diets of fruit flies. In a rare rebuke to the notion that restricting calories can increase life spans, researchers found that it may be a matter of forgoing specific foods, rather than just eating less, that aids longevity.

The study only looked at a couple of sparse diets, and it remains to be seen if such findings will hold true in further animal tests, let alone on humans, the researchers caution. But similar types of experiments have driven a strong interest in calorie restrictive diets, including an ongoing study sponsored by the National Institute of Aging (NIA). Researchers in Boston and elsewhere are currently investigating whether cutting back on calories can slow down the aging process in middle-aged men and women.

Linda Partridge, PhD, a researcher at University College, London who led the new study on fruit flies, said that her findings are in contrast to what has been shown previously. Since the 1930s, researchers have tested just about every animal possible and found that a calorie is a calorie when it comes to extending lives. "It really doesn't matter how it's achieved, what matters is that calories are restricted," she said.

But citing an increasing number of experiments done by other teams, Partridge said that some calories might count more than others. As part of the study, which was published today in online medical journal, PloS Biology, Partridge and colleagues tested two separate diets on a common type of fruit fly, known as drosophila. Some of the flies were given yeast, which is high in proteins and fat—a type of Zone diet for bugs. The others were fed sugar, a source of carbohydrates.

In each case, the flies were provided with fewer calories than normal. Reducing both nutrients led to longer lives, but restricting yeast increased a fly's life span by a further 60 percent compared to restricting sugar. Is it possible that a low-carb diet is bad for longevity?

"Mammals and flies are much different in that regard," said Partridge. Insects, unlike people, are not at risk for obesity and diabetes, meaning that they naturally benefit from sugary diets. At this point, Partridge said it is hard to tell what type of diet will keep us living longer. "The jury is still out," she said.

Eric Ravussin, PhD, of the Pennington Biomedical Research Center, who was not involved in the study, said that measuring calories in fruit flies is no easy task, which makes it hard to tell if specific foods can promote longer lives. Still, he has long been skeptical that all calories are the same. In looking at the problems associated with over eating, for example, "we know the origin of calories can be important," he said.

The recent findings, he added, could spur research that may find some foods are better than others, raising the hope for big eaters that life is worth living. But as one of the researchers involved in the NIA sponsored study on calorie restriction, Ravussin has watched an overwhelming majority of volunteers stick to a nutritiously balanced diet. Despite being asked to cut back on their calories by 10 to 30 percent, many have coped just fine. "I was surprised," said Ravussin.

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